Poster électronique

Evaluation non invasive du risque d'athérosclérose au cours de la spondylarthrite ankylosante (SA)
S. Chaabouni, W. Hamdi, E. Ben Youssef, I. Zouch, MM. Ghannouchi, MM. Kchir, M. Chelli Bouaziz - Tunis - Tunisie
Congrès 2011
Résumé
Objectifs
Evaluer l'épaisseur intima-média carotidienne chez des patients atteints de SA et la comparer à des sujets témoins.
Matériels et méthodes
Ont été inclus dans cette étude transversale, 60 patients (48 hommes et 12 femmes), atteints de SA répondant aux critères de New York modifiés et 60 témoins appariés pour l'âge et le sexe. Les facteurs de risque classiques d'athérosclérose ont été recherchés : hypertension artérielle, indice de masse corporel, tabagisme, diabète, dyslipidémie. Nous avons mesuré, par une échographie de haute résolution (15 M Hz), l'épaisseur intima-media (EIM) des carotides droite et gauche.
Résultats
L'âge moyen des patients était de 36 ± 11ans. L'ancienneté moyenne de la maladie était de 13,1±8,5 ans. L'âge de début moyen était de 25,1± 11,2 ans. La durée d'évolution de la SA était en moyenne de 13,1 ± 8,5 années. Les deux groupes étaient comparables quant aux facteurs de risque classique d'athérosclérose. L'EIM moyenne était de 0,51±0,12 mm pour le groupe SA et 0,39± 0,09 pour le group témoin (p< 0.0001).
Conclusion
Notre étude confirme que le risque d'athérosclérose est plus important chez les patients atteints de SA. La mesure de l'EIM par l'échographie haute résolution est une méthode sensible, fiable, non invasive et reproductible et permet un suivi à long terme de ces patients.
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