Poster électronique

L’efficacité de l’IRM dans l’évaluation de la réponse tumorale à la chimiothérapie néo-adjuvante (CNA)
M. Nadrljanski, Z. Milosevic, N. Borojevic - Belgrade - Serbie
Congrès 2010
Résumé
Objectifs
L’objectif de la recherche était d’analyser l’efficacité et la précision de l’IRM dans le suivi de la réponse tumorale à la CNA, chez les patientes avec le cancer du sein – le changement de taille et de volume de la tumeur, les paramètres de la réponse tumorale à la CNA, influençant ainsi la décision chirurgicale.
Matériels et méthodes
Nous avons analysé les résultats publiés de 16 essais cliniques, effectués pendant la période : 1994 - 2010. Il y avait 587 patientes analysées dans les essais, toutes examinées avant et après la CNA. Il est important de noter que tous les essais ont été conclus avec l’efficacité prouvée de l’IRM dans le suivi de la réponse tumorale.
Résultats
L'IRM donne des informations anatomiques claires et précises, importantes pour la planification préopératoire en termes de prise de décision chirurgicale, entre la tumorectomie et la mastectomie. Par rapport à l’examen clinique, l'échographie et la mammographie, l'IRM est considérée comme la méthode la plus précise pour l’estimation de la tumeur résiduelle après la CNA. Le changement de volume peut fournir une évaluation de l’efficacité du traitement plus sensible que le changement du diamètre.
Conclusion
L’IRM est considérée comme prédictive en termes de survie sans récidive, en comparaison avec d’autres méthodes.
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